OSU:pro

Current OSU Appointment

Associate Professor, Biochemistry Administration

Degrees

1986	B.S., Fudan University, Chemistry

1989	M.S., Fudan University, Physical Chemistry

1997	Ph.D., The Pennsylvania State University, Biological Chemistry

2000	Postdoctoral, Harvard Medical School, Biological Chemistry

Honors

1996	Bristol-Meyers Squibb Travel Award.

1997	Award Recipient. 12th Annual Graduate Student Research Exhibition. The Pennsylvania State University, University Park, PA, United States.

1999	Postdoctoral Fellowship.

2005	NSF CAREER Award.

2006	Dean's Award for Classroom Teaching for Faculty.

2007	Dean's Award for Undergrad Research Mentoring. The Ohio State University, Columbus, OH, United States.

Outreach

Undergraduate Biochemistry Club field trip
Project Dates: - present
Description: Visit to Eli Lilly & Co. in Indianapolis, IN

Undergraduate Biochemistry Club
Project Dates: - present
Description: Took 23 undergraduate students from our Undergraduate Biochemistry club to visit Omeris, a biotechnology company and incubator in Ohio on March 6, 2007.

Peer Reviewed Journal Articles

Fiala, Kevin, A; Abdel-Gawad, Wissam; Suo, Zucai. 2004. Pre-steady-state kinetic studies of the fidelity and mechanism of polymerization catalyzed by truncated human DNA polymerase lambda. Biochemistry. Vol. 43, no. 21: 6751-62.

Fiala, Kevin, A; Suo, Zucai. 2004. Mechanism of DNA polymerization catalyzed by Sulfolobus solfataricus P2 DNA polymerase IV. Biochemistry. Vol. 43, no. 7: 2116-25.

Fiala, Kevin, A; Suo, Zucai. 2004. Pre-steady-state kinetic studies of the fidelity of Sulfolobus solfataricus P2 DNA polymerase IV. Biochemistry. Vol. 43, no. 7: 2106-15.

Roettger, Michelle, P; Fiala, Kevin, A; Sompalli, Susmitha; Dong, Yuxia; Suo, Zucai. 2004. Pre-steady-state kinetic studies of the fidelity of human DNA polymerase mu. Biochemistry. Vol. 43, no. 43: 13827-38.

Suo, Zucai. 2005. Thioesterase portability and peptidyl carrier protein swapping in yersiniabactin synthetase from Yersinia pestis. Biochemistry. Vol. 44, no. 12: 4926-38.

Duym, Wade, W; Fiala, Kevin, A; Bhatt, Nikunj; Suo, Zucai. 2006. Kinetic effect of a downstream strand and its 5'-terminal moieties on single nucleotide gap-filling synthesis catalyzed by human DNA polymerase lambda. The Journal of biological chemistry. Vol. 281, no. 47: 35649-55.

Fiala, Kevin, A; Duym, Wade, W; Zhang, Jun; Suo, Zucai. 2006. Up-regulation of the fidelity of human DNA polymerase lambda by its non-enzymatic proline-rich domain. The Journal of biological chemistry. Vol. 281, no. 28: 19038-44.

Brown, Jessica, A; Duym, Wade, W; Fowler, Jason, D; Suo, Zucai. 2007. Single-turnover kinetic analysis of the mutagenic potential of 8-oxo-7,8-dihydro-2'-deoxyguanosine during gap-filling synthesis catalyzed by human DNA polymerases lambda and beta. Journal of molecular biology. Vol. 367, no. 5: 1258-69.

Fiala, Kevin, A; Brown, Jessica, A; Ling, Hong; Kshetry, Ajay, K; Zhang, Jun; Taylor, John-Stephen; Yang, Wei; Suo, Zucai. 2007. Mechanism of template-independent nucleotide incorporation catalyzed by a template-dependent DNA polymerase. Journal of molecular biology. Vol. 365, no. 3: 590-602.

Fiala, Kevin, A; Hypes, Cameron, D; Suo, Zucai. 2007. Mechanism of abasic lesion bypass catalyzed by a Y-family DNA polymerase. The Journal of biological chemistry. Vol. 282, no. 11: 8188-98.

Fiala, Kevin, A; Suo, Zucai. 2007. Sloppy bypass of an abasic lesion catalyzed by a Y-family DNA polymerase. The Journal of biological chemistry. Vol. 282, no. 11: 8199-206.