Dr Douglas Robert Pfeiffer
310A Hamilton Hall
1645 Neil Ave
Columbus, OH 43210
Phone: (614) 292-8774
Email: pfeiffer.17@osu.edu
Current OSU Appointments
Professor, Molecular & Cellular Biochemistry
Professor, Internal Medicine
Degrees
| 1967 | B.A., Iowa State University, Genetics |
| 1968 | B.A., Coe College, Chemistry Physics |
| 1968 | B.A., Coe College, Biology |
| 1973 | Ph.D., Wayne State University, Chemistry (Biochemistry) |
Editorial Activities
Editor
| 1988 | Monograph "Cellular Ca2+ Regulation", Plenum Press, New York, New York. |
Editorial Board
| 2007 | Chemistry and Physics of Lipids. |
| 2007 | Journal of Biological Chemistry. |
Grant Reviewer
| 2007 | NIH, Numerous Site Visits and Special Study Section Assignments/Chairmanships. |
| 1998 - 2001 | NIH, Molecular, Cellular and Developmental Neurosciences-2 Study Sections. |
| 1993 | American Heart Association, Ohio Affiliate Peer Review. |
| 1992 - 1995 | American Heart Association, National Cell Transport and Metabolism Research Study Committee. |
| 1992 - 1995 | Department of Veterans Affairs Merit Board for Basic Sciences. |
| 1990 | NIH, Physical Biochemistry Study Section. |
| 1989 | NIH, Physical Biochemistry Study Section. |
| 1985 | NIH, Physiological Chemistry Study Section. |
| 1984 | NIH, Physical Biochemistry Study Section. |
| 1983 | NIH, Physical Biochemistry Study Section. |
Journal Reviewer
| 2007 | Archives of Biochemistry and Biophysics. |
| 2007 | Biochemical Pharmacology. |
| 2007 | Biochemistry. |
| 2007 | Biochimica et Biophysica Acta. |
| 2007 | Chemistry. |
| 2007 | Journal of Biological Chemistry. |
| 2007 | Journal of Membrane Biology. |
| 2007 | Journal of Neurochemistry. |
| 2007 | Journal of Theoretical Biology. |
Honors
| Phi Lambda Epsilon Honorary Chemical Society. |
| 1967 | NSF-UGR Award. |
| 1971 - 1972 | Noeller Fellowship in Chemistry. |
| 1974 | Graduate School Fellowship in Biochemistry. |
| 1984 | Visiting Professor. |
| 1993 | Visiting Professor. |
Memberships
| Member. American Society of Biochemistry and Molecular Biology |
| Member. American Chemical Society |
| Member. American Chemical Society |
| Member. American Association for the Advancement of Science |
| Member. The Biophysical Society |
| 1979 - 1980 | Member. The Hormel Institute. EEO-AA Committee |
| 1979 - 1980 | Member. The Hormel Institute. Civil Service Committee |
| 1979 - 1980 | Member. The Hormel Institute. Seminar Committee |
| 1979 - 1980 | Member. The Hormel Institute. Faculty Search Committee |
| 1979 - 1989 | Safety Officer. The Hormel Institute. Radioactivity Safety Officer |
| 1980 - 1981 | Member. The Hormel Institute. Training Grant Committee |
| 1981 - 1982 | Member. The Hormel Institute. Long Range Planning Committee |
| 1982 - 1983 | Member. The Hormel Institute. Guest Professor Committee |
| 1982 - 1983 | Member. The Hormel Institute. Public Relations Committee |
| 1983 - 1985 | Member. The Hormel Institute. Library Committee |
| 1983 - 1991 | Member. Notes:Directed a major collaborative research effort which was funded as a Program Project Grant from the National Institutes of Health, Heart, Lung and Blood Institute. The annual direct cost budget was on the order of $1,200,000. Normally, ten faculty members from my home and collaborative institutions were involved,appointed |
| 1984 - 1986 | Member. Hormel Institute Senate |
| 1984 - 1992 | Member. Program Project Grant HL 08214 Steering Committee |
| 1984 - 1985 | Member. The Hormel Institute. Planning Committee |
| 1984 - 1985 | Member. The Hormel Institute. Finance Committee |
| 1984 - 1987 | Member. The Hormel Institute. Safety Committee |
| 1984 - 1989 | Representative. The Hormel Institute. Institute Controlled Substances |
| 1985 - 1986 | Member. The Hormel Institute. Travel Award Committee |
| 1986 - 1987 | Member. The Hormel Institute. Equipment Distribution Committee |
| 1986 | Co-Organizer. Satellite Symposia on The Regulation of Cellular Ca2+ Homeostasis, held during the 30th International Congress of the Union of Physiological Sciences. Chairman of the session 'CA2+ transport by mitochondria', Seattle |
| 1987 - 1988 | Member. The Hormel Institute. Instrument Development Committee |
| 1987 - 1988 | Member. The Hormel Institute. Postdoctoral Matters Committee |
| 1988 | Member. The Hormel Institute. Seminar Committee |
| 1988 - 1989 | Member. The Hormel Institute. Finance Committee |
| 1992 | Member. EBEC Satellite Symposium on Mitochondrial Cation Transport. 7th EBEC Conference, Helsinki, Finland |
| 1993 | Member. The Ohio State University. Department of Molecular and Cellular Biochemistry Promotion and Tenure Committee |
| 1993 | Member. Scientific Committee, Workshop entitled New Perspectives in Mitochondrial Research, 2nd IUBMB Conference on Biochemistry of Cell Membranes, Chairman of the session entitled Mitochondria and Cell Death, September, Padova, Italy |
| 1994 | Member. The Ohio State University. Department of Medical Biochemistry Faculty Search Committee |
| 1995 - 1997 | Member. The Ohio State University. The Ohio State Biochemistry Program Curriculum Committee |
| 1995 - present | Member. IUBMB Conferences on Mitochondrial Research. Scientific Committee |
| 1996 | Session Co-Chair. Mitochondrial Channels, Biophysical Society Annual Meeting |
| 1996 | Session Co-Chair. Membrane Transport, Biophysical Society Annual Meeting |
| 1996 - 1997 | Member. The Ohio State University. Biophysics Program Curriculum Committee |
| 1997 | Member. The Ohio State University. College of Medicine Research Committee |
| 1997 | Consultant. Astra Arcus Incorporated |
| 1998 - 2001 | Member. The Ohio State University. College of Medicine Research Committee |
| 1998 | Member. Albany Conference on Mitochondrial Research. Program Committee |
| 2000 | Member. Albany Conference on Mitochondrial Research. Program Committee |
| 2000 - 2003 | Member. The Ohio State University. College of Medicine and Public Health, Faculty Council |
| 2000 - 2003 | Member. The Ohio State University. University Senate |
| 2002 | Session Co-Chair. Biophysical Society Annual Meeting, Mitochondria and Apoptosis |
Peer Reviewed Journal Articles
Bernardi, Paolo; Broekemeier, Kimberly M.; Pfeiffer, Douglas R. 1994. Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin-sensitive pore in the inner mitochondrial membrane. Journal of Bioenergetics and Biomembranes. Vol. 26, no. 5: 509-517.
Broekemeier, Kimberly M.; Krebsbach, Randy J.; Pfeiffer, Douglas R. 1994. Inhibition of the mitochondrial Ca-2+ uniporter by pure and impure ruthenium red. Molecular and Cellular Biochemistry. Vol. 139, no. 1: 33-40.
Erdahl, Warren L.; Chapman, Clifford J.; Taylor, Richard W.; Pfeiffer, Douglas R. 1994. Ca-2+ transport properties of ionophores A23187, ionomycin, and 4-bra23187 in a well defined model system. Biophysical Journal. Vol. 66, no. 5: 1678-1693.
Gordon, Joel A.; Broekemeier, Kimberly M.; Spector, Arthur A.; Pfeiffer, Douglas R. 1994. Mitochondrial metabolism of 12- and 15-hydroxyeicosatetraenoic acids. Journal of Lipid Research. Vol. 35, no. 4: 698-708.
Novgorodov, Sergei A.; Gudz, Tatyana I.; Brierley, Gerald P.; Pfeiffer, Douglas R. 1994. Magnesium ion modulates the sensitivity of the mitochondrial permeability transition pore to cyclosporin A and Adp. Archives of Biochemistry and Biophysics. Vol. 311, no. 2: 219-228.
Broekemeier, Kimberly M.; Pfeiffer, Douglas R. 1995. Inhibition of the mitochondrial permeability transition by cyclosporin A during long time frame experiments: Relationship between pore opening and the activity of mitochondrial phospholipases. Biochemistry. Vol. 34, no. 50: 16440-16449.
Pfeiffer, Douglas R.; Gudz, Tatyana I.; Novgorodov, Sergei A.; Erdahl, Warren L. 1995. The peptide mastoparan is a potent facilitator of the mitochondrial permeability transition. Journal of Biological Chemistry. Vol. 270, no. 9: 4923-4932.
Erdahl, Warren L.; Chapman, Clifford J.; Wang, Exing; Taylor, Richard W.; Pfeiffer, Douglas R. 1996. Ionophore 4-bra23187 transports Zn-2+ and Mn-2+ with high selectivity over Ca-2+. Biochemistry. Vol. 35, no. 43: 13817-13825.
Jung, Dennis W.; Chapman, Clifford J.; Baysal, Kemal; Pfeiffer, Douglas R.; Brierley, Gerald P. 1996. On the use of fluorescent probes to estimate free Mg-2+ in the matrix of heart mitochondria. Archives of Biochemistry and Biophysics. Vol. 332, no. 1: 19-29.
Jung, Dennis W.; Bradshaw, Patrick C.; Pfeiffer, Douglas R. 1997. Properties of a cyclosporin-insensitive permeability transition pore in yeast mitochondria. Journal of Biological Chemistry. Vol. 272, no. 34: 21104-21112.
Litsky, Monica L.; Pfeiffer, Douglas R. 1997. Regulation of the mitochondrial Ca-2+ uniporter by external adenine nucleotides: The uniporter behaves like a gated channel which is regulated by nucleotides and divalent cations. Biochemistry. Vol. 36, no. 23: 7071-7080.
Thomas, Timothy P.; Wang, Exing; Pfeiffer, Douglas R.; Taylor, Richard W. 1997. Evidence against formation of A23187 dimers and oligomers in solution: Photo-induced degradation of ionophore A23187. Archives of Biochemistry and Biophysics. Vol. 342, no. 2: 351-361.
Wang, Exing; Taylor, Richard W.; Pfeiffer, Douglas R. 1998. Mechanism and specificity of lanthanide series cation transport by ionophores A23187, 4-bra23187, and ionomycin. Biophysical Journal. Vol. 75, no. 3: 1244-1254.
Erdahl, Warren L.; Chapman, Clifford J.; Taylor, Richard W.; Pfeiffer, Douglas R. 2000. Ionomycin, a carboxylic acid ionophore, transports Pb2+ with high selectivity. Journal of Biological Chemistry. Vol. 275, no. 10: 7071-7079.
Bradshaw, Patrick C.; Jung, Dennis W.; Pfeiffer, Douglas R. 2001. Free fatty acids activate a vigorous Ca2+:2h+ antiport activity in yeast mitochondria. Journal of Biological Chemistry. Vol. 276, no. 44: 40502-40509.
Mannella, Carmen A.; Pfeiffer, Douglas R.; Bradshaw, Patrick C.; Moraru, Ion I.; Slepchenko, Boris; Loew, Leslie M.; Hsieh, Chyong-ere; Buttle, Karolyn; Marko, Michael. 2001. Topology of the mitochondrial inner membrane: Dynamics and bioenergetic implications. IUBMB Life. Vol. 52, no. 3-5: 93-100.
Pfeiffer, Douglas R.; Gunter, Thomas E.; Eliseev, Roman; Broekemeier, Kimberly M.; Gunter, Karlene K. 2001. Release of Ca2+ from mitochondria via the saturable mechanisms and the permeability transition. IUBMB Life. Vol. 52, no. 3-5: 205-212.
Wang, Exing; Erdahl, Warren L.; Hamidinia, Shawn A.; Chapman, Clifford J.; Taylor, Richard W.; Pfeiffer, Douglas R. 2001. Transport properties of the calcium ionophore Eth-129. Biophysical Journal. Vol. 81, no. 6: 3275-3284.
Broekemeier, Kimberly, M; Iben, James, R; LeVan, Emily, G; Crouser, Elliott, D; Pfeiffer, Douglas R. 2002. Pore formation and uncoupling initiate a Ca2+-independent degradation of mitochondrial phospholipids. Biochemistry. Vol. 41, no. 24: 7771-80.
Crouser, Elliott, D; Julian, Mark, W; Blaho, Dorottya, V; Pfeiffer, Douglas R. 2002. Endotoxin-induced mitochondrial damage correlates with impaired respiratory activity. Critical care medicine. Vol. 30, no. 2: 276-84.
Crouser, Elliott, D; Julian, Mark, W; Joshi, Mandar, S; Bauer, John, A; Wewers, Mark, D; Hart, Judith, M; Pfeiffer, Douglas R. 2002. Cyclosporin A ameliorates mitochondrial ultrastructural injury in the ileum during acute endotoxemia. Critical care medicine. Vol. 30, no. 12: 2722-8.
Hamidinia, Shawn, A; Shimelis, Olga, I; Tan, Bo; Erdahl, Warren, L; Chapman, Clifford, J; Renkes, Gordon, D; Taylor, Richard, W; Pfeiffer, Douglas R. 2002. Monensin mediates a rapid and selective transport of Pb(2+). Possible application of monensin for the treatment of Pb(2+) intoxication. The Journal of biological chemistry. Vol. 277, no. 41: 38111-20.
Crouser, Elliott, D; Gadd, Martha, E; Julian, Mark, W; Huff, Jennifer, E; Broekemeier, Kimberly, M; Robbins, Karen, A; Pfeiffer, Douglas R. 2003. Quantitation of cytochrome c release from rat liver mitochondria. Analytical biochemistry. Vol. 317, no. 1: 67-75.
Crouser, Elliott, D; Julian, Mark, W; Huff, Jennifer, E; Joshi, Mandar, S; Bauer, John, A; Gadd, Martha, E; Wewers, Mark, D; Pfeiffer, Douglas R. 2004. Abnormal permeability of inner and outer mitochondrial membranes contributes independently to mitochondrial dysfunction in the liver during acute endotoxemia. Critical care medicine. Vol. 32, no. 2: 478-88.
Hamidinia, Shawn, A; Tan, Bo; Erdahl, Warren, L; Chapman, Clifford, J; Taylor, Richard, W; Pfeiffer, Douglas R. 2004. The ionophore nigericin transports Pb2+ with high activity and selectivity: a comparison to monensin and ionomycin. Biochemistry. Vol. 43, no. 50: 15956-65.
Jung, Dennis, W; Bradshaw, Patrick, C; Litsky, Monica; Pfeiffer, Douglas R. 2004. Ca2+ transport in mitochondria from yeast expressing recombinant aequorin. Analytical biochemistry. Vol. 324, no. 2: 258-68.
Bradshaw, Patrick C.; Pfeiffer, Douglas R. 2006. Loss of Nad(h) from swollen yeast mitochondria. BMC Biochemistry. Vol. 7.
Bradshaw, Patrick C.; Pfeiffer, Douglas R. 2006. Release of Ca2+and Mg2+from yeast mitochondria is stimulated by increased ionic strength. BMC Biochemistry. Vol. 7.
Gadd, Martha, E; Broekemeier, Kimberly, M; Crouser, Elliott, D; Kumar, Jitendra; Graff, Gustav; Pfeiffer, Douglas R. 2006. Mitochondrial iPLA2 activity modulates the release of cytochrome c from mitochondria and influences the permeability transition. The Journal of biological chemistry. Vol. 281, no. 11: 6931-9.
Hamidinia, Shawn, A; Erdahl, Warren, L; Chapman, Clifford, J; Steinbaugh, Gregory, E; Taylor, Richard, W; Pfeiffer, Douglas R. 2006. Monensin improves the effectiveness of meso-dimercaptosuccinate when used to treat lead intoxication in rats. Environmental health perspectives. Vol. 114, no. 4: 484-93.
Hamidinia, Shawn, A; Steinbaugh, Gregory, E; Erdahl, Warren, L; Taylor, Richard, W; Pfeiffer, Douglas R. 2006. Selective transport of Pb2+ and Cd2+ across a phospholipid bilayer by a cyclohexanemonocarboxylic acid-capped 15-crown-5 ether. Journal of inorganic biochemistry. Vol. 100, no. 3: 403-12.
Chen, Yeong-Renn; Chen, Chwen-Lih; Pfeiffer, Douglas, R; Zweier, Jay L. 2007. Mitochondrial complex II in the post-ischemic heart: oxidative injury and the role of protein S-glutathionylation. The Journal of biological chemistry. Vol. 282, no. 45. (November 9). (IF: 5.808)
Positions
| 1967 | Undergraduate Research, Iowa State University, Department of Genetics. Ames, IA, United States. |
| 1968 | Senior Research, Coe College, Chemistry Department. Cedar Rapids. |
| 1969 - 1972 | Research Assistant, Wayne State University. Detroit, MI, United States. |
| 1973 | Postdoctoral Fellow, Wayne State University. Detroit. |
| 1974 - 1975 | Postdoctoral Fellow, University of Wisconsin, Institute for Enzyme Research. Madison, WI, United States. |
| 1976 | Research Assistant Professor, University of Wisconsin, Institute for Enzyme Research. Madison, WI, United States. |
| 1977 - 1980 | Assistant Professor, University of Minnesota, The Hormel Institute. |
| 1981 - 1985 | Associate Professor, University of Minnesota, The Hormel Institute. |
| 1986 - 1992 | Professor (Adjunct), Mayo Medical School, Department of Biochemistry and Molecular Biology. Rochester, Minnesota. |
| 1986 - 1992 | Professor, University of Minnesota, The Hormel Institute. |
| 2005 - present | Director, The Ohio State University, Institue for Mitochondrial Biology. Columbus, OH, United States. |
| 2005 - present | Professor, The Ohio State University, Department of Internal Medicine. Columbus, OH, United States. |
Presentations
Other Presentations
Local
Dr. Douglas Robert Pfeiffer. 1973. Some Effects of Ca2+ on the Properties of Adrenal Cortex Mitochondria. (August 30)
DR Pfeiffer, SM Hutson and HA Lardy. 1974. The Use of Divalent Cation Ionophores to Investigate the Postulated Membrane Potential in Mitochondria. Presented at Am. Chem. Soc., Div. of Biol. Chem., 168th National Meeting. (August 30)
PW Reed and DR Pfeiffer. 1974. Divalent Cation Transport by Antibiotic A23187. Presented at The Annual New England Bioengineering Conference 2. (August 30)
DR Pfeiffer and HA Lardy. 1976. Some Properties of Ionophore A23187. Presented at Proceedings of the ICN-UCLA Winter Conference on Molecular and Cellular Biology. (August 30)
Dr. Douglas Robert Pfeiffer. 1976. Primary and Secondary Ion Movements in Mitochondria Treated with A23187. (August 30)
DR Pfeiffer and HA Lardy. 1977. Ionophore A23187: Cation Binding and Transport Properties. Presented at The New York Academy of Sciences, Conference on Calcium Transport and Cell Function. (August 30)
Dr. Douglas Robert Pfeiffer. 1977. Inhibition by N-Ethylmaleimide of Ca2+ Uptake and Retention in Rat Liver Mitochondria. (August 30)
DR Pfeiffer, PC Schmid and HHO Schmid. 1978. Membrane Ca2+ Loading Stimulates the Release of Free Fatty Acids from Mitochondria. (August 30)
Dr. Douglas Robert Pfeiffer. 1978. Exploring the Chemical and Biochemical Bases for the Biological Activities of A23187. Presented at Joint Central-Great Lakes American Chemical Society Meeting. (August 30)
Dr. Douglas Robert Pfeiffer. 1978. Recent Studies on the Biochemical Properties of Selected Ionophores. Presented at I.C.A.A.C. Annual Meeting. Atlanta, GA. (August 30)
Dr. Douglas Robert Pfeiffer. 1979. Invited participant in the Scientific Working Conference on Cystic Fibrosis. Presented at NIH and the Cystic Fibrosis Foundation. Brownsville, TX. (August 30)
DR Pfeiffer, MC Beatrice and JW Palmer. 1980. The Mechanism of Ca2+ Release From Liver and Heart Mitochondria. (August 30)
Dr. Douglas Robert Pfeiffer. 1980. Effects of Ionomycin, A Novel Carboxylic Acid Ionophore, Upon Energy Dependent Ca2+ Transport in Rat Liver Mitochondria. (August 30)
Dr. Douglas Robert Pfeiffer. 1980. Lipid Composition and Na+-K+-ATPase Activity in Lens During Cataracto-genesis. Presented at A.R.V.O. Annual Meeting. Kissimmee, FL. (August 30)
PC Schmid, DR Pfeiffer and HHO Schmid. 1980. Permeability Changes Mitochondrial Membranes Are Related to the Levels of Their Constituent Lysophosphatidyl Ethanolamines. (August 30)
DR Pfeiffer, JW Palmer, MC Beatrice, DE Epps, PC Schmid and HHO Schmid. 1981. Regulation of Membrane Permeability in Mitochondria. Presented at 23rd International Congress on the Biochemistry of Lipids. Nyborg, Denmark. (August 30)
Dr. Douglas Robert Pfeiffer. 1981. Lipid Composition and (Na+-K+)-ATPase in Triparanol Cataract. (August 30)
PC Sen and DR Pfeiffer. 1981. Loss of (Na+-K+)-ATPase Activity During Cataract Formation: Properties of the Lens Enzyme. Presented at Third International Symposium on (Na+-K+)- ATPase, Yale University. (August 30)
RF Kauffman and DR Pfeiffer. 1981. On the Location and Dynamics of Ionophore A23187 Within Phospholipid Bilayers. (August 30)
Dr. Douglas Robert Pfeiffer. 1982. The Mechanism and Regulation of Ca2+ Efflux from Mitochondria. Presented at 12th Annual Steenbock Symposium, Biochemistry of Metabolic Processes, University of Wisconsin. WI. (August 30)
Dr. Douglas Robert Pfeiffer. 1982. The Relationship Between Ca2+ Flux and Permeability Modulation in the Inner Mitochondrial Membrane. Presented at Symposium on Membrane Damage and Repair, 73rd Annual Meeting of the American Oil Chemists' Society. Toronto, Canada. (August 30)
JW Palmer, DE Epps, HHO Schmid and DR Pfeiffer. 1982. Inhibition of Phospholipase A2 Dependent Permeability Changes in Mitochondria by N-Acylethanolamines, Compounds Produced by Infarcted Dog Heart. (August 30)
MC Beatrice, DL Stiers and DR Pfeiffer. 1982. Prevention of `Ca2+ Cycling' in Mitochondria Does Not Separate Ca2+ Release Induced by Oxalacetate, Phosphate or t-Butyl-hydroperoxide from Increased Inner Membrane Permeability. (August 30)
PC Sen and DR Pfeiffer. 1982. Characterization of Partially Purified Na+, K+-ATPase from Porcine Lens. (August 30)
DR Pfeiffer, CL Chapman, RW Taylor and JL Laing. 1983. Monovalent Cation-A23187 Equilibrium in MeOH-H2O Solutions and on Phospholipid Vesicles. Presented at 1st International Conference on Bioinorganic Chemistry. Florence, Italy. (August 30)
Dr. Douglas Robert Pfeiffer. 1983. The Regulation of Ca2+ Efflux in Mitochondria. Presented at Gordon Research Conference on Energy Coupling Mechanisms. Andover, NH. (August 30)
KM Broekemeier, PC Schmid, HHO Schmid and DR Pfeiffer. 1983. Properties of Rat Liver Mitochondrial Phospholipase A2. (August 30)
MC Beatrice, DL Stiers and DR Pfeiffer. 1983. The Involvement of Reduced Glutathione Levels in Ca2+ Release from Mitochondria. (August 30)
PC Sen, RJ Krebsbach and DR Pfeiffer. 1983. Effects of Sodium Thiocyanate on Na+, K+-ATPase from Porcine Lens. (August 30)
DR Pfeiffer and CJ Chapman. 1984. Equilibria Between Ionophore A23l87 and Monovalent Cations: Effects of Membrane Association and Solvent Composition. (August 30)
RW Taylor, JL Laing, DR Pfeiffer and CJ Chapman. 1985. Spectrophotometric and Fluorometric Determination of Stability Constants of Ionophore A23187 with Li+ and Na+. Presented at XIIth Meeting of the Federation of Analytical Chemistry and Spectroscopy Societies. Philadelphia, PA. (August 30)
G Fiskum, DR Pfeiffer, KM Broekemeier and B Baroody. 1985. Calcium Buffering Characteristics and Phospholipase A Activities of Rat Brain Mitochondria. (August 30)
M Reers, DE Murray and DR Pfeiffer. 1985. A Novel Inhibitor of Mitochondrial Phospholipase A2. Presented at 13th International Congress of Biochemistry. Amsterdam. (August 30)
MP Cleary, L Lennie, EW Thompson and DR Pfeiffer. 1985. Changes in Liver Mitochondria Content and O2 Consumption Induced by Dehydroepiandrosterone (DHEA) Treatment. Presented at The American Diabetes Association Joint Conference on Obesity and Non-Insulin Dependent Diabetes Mellitus. Toronto, Canada. (August 30)
WW Riley, Jr and DR Pfeiffer. 1985. Hypolipidemic Drugs Are Ca2+ Releasing Agents in Rat Liver Mitochondria. (August 30)
WW Riley, Jr and DR Pfeiffer. 1985. Relationships Between Ca2+ Release, Ca2+ Cycling, and Ca2+ Mediated Permeability Changes in Mitochondria. (August 30)
AK Puri, CJ Chapman, RW Taylor and DR Pfeiffer. 1986. . Presented at A Basis for Divalent Cation Selective Transport by Ionophore A23187. (August 30)
Dr. Douglas Robert Pfeiffer. 1986. Permeabililty Pathways of Ca2+ Efflux. Presented at The International Union of Physiological Sciences Satellite Symposium on Regulation of Cellular Ca2+ Homeostasis. Seattle, WA. (August 30)
Dr. Douglas Robert Pfeiffer. 1986. The Effect of Ca2+ and AcylCoA:Lysophospholipid-Acyltransferase Inhibitors on Permeability Properties of the Liver Mitochondrial Inner Membrane. Presented at The Mitochondrion, John Hopkins University. (August 30)
M Reers, DE Murray and DR Pfeiffer. 1986. Potent Inhibition of Mitochondrial Phospholipase A2 by Monolysocardiolipin. (August 30)
TP Thomas, DR Pfeiffer and RW Taylor. 1987. Complexation and Dissociation Kinetics of Ionophore A23187 with Ni2+ in 80% Methanol-Water. (August 30)
U Igbavboa and DR Pfeiffer. 1987. Reverse Uniport Dependent Ca2+-Release from Mitochondria: Inhibition by EGTA Plus Mg2+. (August 30)
Dr. Douglas Robert Pfeiffer. 1987. Mitochondrial Phospholipase A2 and Acyltransferases, Function and Regulation. Presented at The Hormel Institute Conference on Membrane Lipids. Austin, TX. (August 30)
KM Broekemeier, ME Dempsey and DR Pfeiffer. 1987. Specific Inhibition by N-ethyl-maleimide of Coenzyme A-Dependent Acylation of Lysophosphatidylcholine in Rat Liver Mitochondria. (August 30)
U Igbavboa and DR Pfeiffer. 1988. Regulation of the Ca2+ Uniporter in Rat Liver Mitochondria. (August 30)
Dr. Douglas Robert Pfeiffer. 1989. Invited participant in the ASBMB Subgroup Meeting, Mitochondrial Membrane Channels. San Francisco, CA. (August 30)
KM Broekemeier, L Carpenter-Deyo, U Igbavboa and DR Pfeiffer. 1990. Protection of Injured Cells by Cyclosporin A. Presented at University of Minnesota Research Showcase, Academia in Review. Minneapolis, MN. (August 30)
Dr. Douglas Robert Pfeiffer. 1992. An Intermembrane Space Peptide which Regulates the Ca2+ Uniporter. Presented at EBEC Satellite Symposium on Mitochondrial Cation Transport. Helsinki. (August 30)
Dr. Douglas Robert Pfeiffer. 1993. The Influence of Medium Composition and Preparative Procedure on Solute Entrapment in Extruded Vesicles. Presented at Workshop on Extruded Liposomes, sponsored by the Membrane Structure and Assembly Subgroup of the Biophysical Society. Washington, DC. (August 30)
Dr. Douglas Robert Pfeiffer. 1994. Long Time Frame Actions of Cyclosporin A and Phospholipase A2 Reaction Products on the Mitochondrial Permeability Transition Pore. Presented at EBEC Colloquium on Coupling Membranes in Cell Death and Aging. Valencia. (August 30)
Dr. Douglas Robert Pfeiffer. 1996. The General Diffusion Pore of the Mitochondrial Inner Membrane. Presented at Great Lakes Association of Clinical Chemists 26th International Congress. Milwaukee, WI. (August 30)
Dr. Douglas Robert Pfeiffer. 1997. Towards Understanding the Physiological Role of the Mitochondrial Permeability Transition Pore. Presented at IUBMB Symposium, New Perspectives in Mitochondrial Research. Padova, Italy. (August 30)
CA Mannella, K Buttle, DR Pfeiffer, BK Rath and M Marko. 1998. . Presented at Mitochondrial Design: Implications for the Structural Basis of the Permeability Transition. (August 30)
Dr. Douglas Robert Pfeiffer. 1998. Recent Progress on the Roles and Properties of Mitochondrial Ca2+ Transport Activities. Presented at Winter Brain Conference. Snowbird, UT. (August 30)
CA Mannella, K Buttle, C Hsieh, DR Pfeiffer, P Bradshaw and M Marko. 2000. Dynamics of Mitochondrial Inner Membrane Folding Inferred from EM Tomography. Presented at 3rd Albany Conference on Frontiers of Mitochondrial Research. (August 30)
OG Ivanova, WL Erdahl, DR Pfeiffer and RW Taylor. 2000. Selective Transport of Pb2+ Across Bilayer Membranes by Pseudo-Macrocyclic Ionophores Monensin and Ionomycin. Presented at XXV International Symposium on Macrocyclic Chemistry. St. Andrews, Scotland. (August 30)
CA Mannella, K Buttle, PC Bradshaw and DR Pfeiffer. 2000. . Presented at Changes in Compartmentation of Yeast Mitochondria after Onset of the Permeability Transition and Osmotic Recontraction. (August 30)
DR Pfeiffer and KM Broekemeier. 2000. Ca2+ Independent Phospholipase A2 (PLA2) of Possible Significance in Initiating Mitochondrial Apoptosis. (August 30)
Dr. Douglas Robert Pfeiffer. 2002. Monensin, a Carboxylic Acid Ionophore Transports Pb2+ with High Selectivity in Model and Biological Systems. Possible use of Monensin in the Treatment of Pb Intoxication. Presented at Gordon Reseach Conference, Colby College Sawyer. NH. (August 30)
O Shimelis, S Hamidinia, W Erdahl, D Pfeiffer, R Taylor. 2002. Selective Transport of Pb2+ by the Polyether Antibiotic Ionophore Monensin. Presented at 35th International Conference on Coordination Chemistry. Heidelberg, German. (August 30)
RW Taylor and DR Pfeiffer. 2002. Anion-Assisted Transport of Heavy Metal and Lanthanide Ions by Polyether Carboxylic Acid Ionophores. Presented at 37th Midwest ACS Regional Meeting. Lawrence, KS. (August 30)