Dr Anthony Brown
60 Rightmire Hall
1060 Carmack Road
Columbus, OH 43210
Phone: (614) 292-1205
Fax: (614) 292-5379
Email: brown.2302@osu.edu
Current OSU Appointment
Associate Professor, Neuroscience
Chapters In Books
Brown, A. & Lasek, R.J. 1990. Studying the cytoskeleton of the squid giant axon. In Squid as experimental animals. Edited by Gilbert, D.L., Adelman, W.J., Jr. & Arnold, J.M. N.Y.: Plenum Publishing Corporation. 235-302.
Black, M.M. & Brown, A. 1993. Sites of microtubule assembly in growing axons. In Neuronal Cytoskeleton: Morphogenesis, Transport and Synaptic Transmission. Edited by Hirokawa, N. Japan Scientific Societies Press, CRC Press. 171-182.
Degrees
| 1982 | B.S.(Honors), University of London, Cell and Molecular Biology |
| 1987 | Ph.D., University of London, Biophysics |
Editorial Activities
Contributing Guest Editor
| 2006 - 2007 | Elsevier's New Encyclopedia of Neuroscience. Wrote entry entitled Slow Axonal Transport. |
Editorial Board
| 2001 | Cell Motility and the Cytoskeleton. |
Journal Reviewer
| 2007 | Molecular Basis of Disease. |
Manuscript Manuscript Reviewer
| 2006 - 2007 | Traffic. (1). |
| 2006 - 2007 | Brain Research. (1). |
| 2006 - 2007 | Journal of Neuroscience Research. (1). |
| 2006 - 2007 | Journal of Cell Biology. (1). |
| 2006 - present | Cell Motility and the Cytoskeleton. (3). |
Manuscript Reviewer
| 2005 - 2006 | Current Biology. |
| 2005 - 2006 | Journal of Neuroscience. |
Memberships
| present | Member. American Society of Cell Biology |
| present | Member. Society for Neuroscience |
| present | Member. American Association for the Advancement of Science |
| 2003 - present | Member. The Ohio State University. NGSP Committee |
| 2003 - present | Member. The Ohio State University. First Year NGSP Students |
| 2005 - 2006 | Member. The Ohio State University, Department of Neuroscience. Ad Hoc Search Committee. Notes:Affirmative Action Rep,,CMN/DNS Joint Faculty Hire |
| 2005 - 2006 | Member. The Ohio State University. Carnegie Initiative on the Doctorate Committee |
| 2005 - 2006 | Member. The Ohio State University, Department of Neuroscience. Education and Curriculum Committee |
| 2005 - 2006 | Member. The Ohio State University, Department of Neuroscience. Executive/ Finance Committee |
| 2005 - 2006 | Member. The Ohio State University, Department of Neuroscience. Faculty Incentives and Salary Recovery Committee |
| 2005 - 2006 | Director. The Ohio State University, the Molecular Neurology Department. CMN/NINDS Imaging Core. Notes:supervised and trained Imaging Core technician |
| 2006 - 2007 | Examiner. Department of Cellular and Molecular Medicine, Univ of Ottowa, Ottowa, Canada. External Examiner, PhD Thesis Committee - Kevin Young |
Peer Reviewed Journal Articles
Brown, A; Eagles, P A. 1986. Squid neurofilaments. Phosphorylation and Ca2+-dependent proteolysis in situ. The Biochemical journal. Vol. 239, no. 1: 191-7.
Baas, P, W; Slaughter, T; Brown, A; Black, M M. 1991. Microtubule dynamics in axons and dendrites. Journal of neuroscience research. Vol. 30, no. 1: 134-53.
Sahenk, Z; Brown, A. 1991. Weak-base amines inhibit the anterograde-to-retrograde conversion of axonally transported vesicles in nerve terminals. Journal of neurocytology. Vol. 20, no. 5: 365-75.
Brown, A; Slaughter, T; Black, M M. 1992. Newly assembled microtubules are concentrated in the proximal and distal regions of growing axons. The Journal of cell biology. Vol. 119, no. 4: 867-82.
Baas, P, W; Ahmad, F, J; Pienkowski, T, P; Brown, A; Black, M M. 1993. Sites of microtubule stabilization for the axon. The Journal of neuroscience : the official journal of the Society for Neuroscience. Vol. 13, no. 5: 2177-85.
Brown, A; Lasek, R J. 1993. Neurofilaments move apart freely when released from the circumferential constraint of the axonal plasma membrane. Cell motility and the cytoskeleton. Vol. 26, no. 4: 313-24.
Brown, A; Li, Y; Slaughter, T; Black, M M. 1993. Composite microtubules of the axon: quantitative analysis of tyrosinated and acetylated tubulin along individual axonal microtubules. Journal of cell science. Vol. 104 ( Pt 2): 339-52.
Brown, A; Lasek, R J. 1995. Polylysine cross-links axoplasmic neurofilaments into tight bundles. Cell motility and the cytoskeleton. Vol. 31, no. 1: 9-21.
Brown, A. 1997. Visualization of single neurofilaments by immunofluorescence microscopy of splayed axonal cytoskeletons. Cell motility and the cytoskeleton. Vol. 38, no. 2: 133-45.
Brown, A. 1998. Contiguous phosphorylated and non-phosphorylated domains along axonal neurofilaments. Journal of cell science. Vol. 111 ( Pt 4): 455-67.
Koehnle, T, J; Brown, A. 1999. Slow axonal transport of neurofilament protein in cultured neurons. The Journal of cell biology. Vol. 144, no. 3: 447-58.
Brown, A. 2000. Slow axonal transport: stop and go traffic in the axon. Molecular Cell Biology. Vol. 1: 153-156.
Wang, L; Ho, C, L; Sun, D; Liem, R, K; Brown, A. 2000. Rapid movement of axonal neurofilaments interrupted by prolonged pauses. Nature cell biology. Vol. 2, no. 3: 137-41.
Wang, L; Brown, A. 2001. Rapid intermittent movement of axonal neurofilaments observed by fluorescence photobleaching. Molecular biology of the cell. Vol. 12, no. 10: 3257-67.
Wang, L. & Brown, A. 2002. Rapid movement of microtubules in axons. Current Biology. Vol. 12: 1496-1501.
Brown, Anthony. 2003. Axonal transport of membranous and nonmembranous cargoes: a unified perspective. The Journal of cell biology. Vol. 160, no. 6: 817-21.
Brown, Anthony. 2003. Live-cell imaging of slow axonal transport in cultured neurons. Methods in cell biology. Vol. 71: 305-23.
Uchida, Atsuko; Brown, Anthony. 2004. Arrival, reversal, and departure of neurofilaments at the tips of growing axons. Molecular biology of the cell. Vol. 15, no. 9: 4215-25.
Brown, Anthony; Wang, Lei; Jung, Peter. 2005. Stochastic simulation of neurofilament transport in axons: the "stop-and-go" hypothesis. Molecular biology of the cell. Vol. 16, no. 9: 4243-55.
Craciun, Gheorghe; Brown, Anthony; Friedman, Avner. 2005. A dynamical system model of neurofilament transport in axons. Journal of theoretical biology. Vol. 237, no. 3: 316-22.
Yan, Yanping; Brown, Anthony. 2005. Neurofilament polymer transport in axons. The Journal of neuroscience : the official journal of the Society for Neuroscience. Vol. 25, no. 30: 7014-21.
Trivedi N, Jung P, Brown A. 2007. Neurofilaments switch between distinct mobile and stationary states during their transport along axons. The Journal of Neuroscience. Vol. 27, no. 3: 507-516. (IF: 7.453)
Yan Y, Jensen K, Brown A. 2007. The polypeptide composition of moving and stationary neurofilaments in cultured sympathetic neurons. Cell motility and the Cytoskeleton. Vol. 64, no. 4: 299-309. (IF: 3.089)
Brown, A. 2008. Slow axonal transport. Encyclopedia of Neuroscience, Larry R. Squire, Academic Press, Oxford. Vol. 9: 1-9.
