OSU:pro

Current OSU Appointments

Professor, Veterinary Biosciences

Professor, Molecular Virology, Immunology & Medical Genetics

Honors

2001	Pfizer Research Award (formerly SmithKline Beecham Research Award).

2006	Charles C Capen Teaching Excellence Award. The Ohio State University, Columbus, OH, United States.

2007

Fellow.

2008	Member, NIH Virology B study section, four-year term 2008-2011. National Institutes of Health. National Institutes of Health, Bethesda, MD, United States. Subject: National Service

Outreach

Association for Women in Science of Central Ohio (AWISCO)
Project Dates: - present
Description: AWISCO - is the Central Ohio chapter of the Association for Women in Science dedicated to the advancement of equity, ethics and full participation of women in science, technology and medicine. Membership in AWISCO is open to women and men.

Website: http://awisco.osu.edu/

Graham School internships
Project Dates: - present
Description: Graham School internships for high school students interested in science and technology. These have been for "disadvantaged" students.

OSU CCC publication
Project Dates: - present
Description: OSU Comprehensive Cancer Center publication of our work displayed to public the role of our retrovirus research as a model for understanding cancer genes

Peer Reviewed Journal Articles

Bohan, C, A; Kashanchi, F; Ensoli, B; Buonaguro, L; Boris-Lawrie, K, A; Brady, J N. 1992. Analysis of Tat transactivation of human immunodeficiency virus transcription in vitro. Gene expression. Vol. 2, no. 4: 391-407.

Boris-Lawrie, K, A; Brady, J, N; Kumar, A. 1992. Sequences within the R region of the long terminal repeat activate basal transcription from the HIV-1 promoter. Gene expression. Vol. 2, no. 3: 215-30.

Boris-Lawrie, K, A; Temin, H M. 1993. Recent advances in retrovirus vector technology. Current opinion in genetics & development. Vol. 3, no. 1: 102-9.

Boris-Lawrie, K; Temin, H M. 1994. The retroviral vector. Replication cycle and safety considerations for retrovirus-mediated gene therapy. Annals of the New York Academy of Sciences. Vol. 716: 59-70; discussion 71.

Boris-Lawrie, K; Temin, H M. 1995. Genetically simpler bovine leukemia virus derivatives can replicate independently of Tax and Rex. Journal of virology. Vol. 69, no. 3: 1920-4.

Boris-Lawrie, K; Altanerova, V; Altaner, C; Kucerova, L; Temin, H M. 1997. In vivo study of genetically simplified bovine leukemia virus derivatives that lack tax and rex. Journal of virology. Vol. 71, no. 2: 1514-20.

Butsch, M; Hull, S; Wang, Y; Roberts, T, M; Boris-Lawrie, K. 1999. The 5' RNA terminus of spleen necrosis virus contains a novel posttranscriptional control element that facilitates human immunodeficiency virus Rev/RRE-independent Gag production. Journal of virology. Vol. 73, no. 6: 4847-55.

Kucerova, L; Altanerova, V; Altaner, C; Boris-Lawrie, K. 1999. Bovine leukemia virus structural gene vectors are immunogenic and lack pathogenicity in a rabbit model. Journal of virology. Vol. 73, no. 10: 8160-6.

Butsch, M; Boris-Lawrie, K. 2000. Translation is not required To generate virion precursor RNA in human immunodeficiency virus type 1-infected T cells. Journal of virology. Vol. 74, no. 24: 11531-7.

Roberts, T, M; Boris-Lawrie, K. 2000. The 5' RNA terminus of spleen necrosis virus stimulates translation of nonviral mRNA. Journal of virology. Vol. 74, no. 17: 8111-8.

Boris-Lawrie, K; Roberts, T, M; Hull, S. 2001. Retroviral RNA elements integrate components of post-transcriptional gene expression. Life sciences. Vol. 69, no. 23: 2697-709.

Pandya, S; Boris-Lawrie, K; Leung, N, J; Akkina, R; Planelles, V. 2001. Development of an Rev-independent, minimal simian immunodeficiency virus-derived vector system. Human gene therapy. Vol. 12, no. 7: 847-57.

Butsch, Melinda; Boris-Lawrie, Kathleen. 2002. Destiny of unspliced retroviral RNA: ribosome and/or virion?. Journal of virology. Vol. 76, no. 7: 3089-94.

Dangel, Andrew, W; Hull, Stacey; Roberts, Tiffiney, M; Boris-Lawrie, Kathleen. 2002. Nuclear interactions are necessary for translational enhancement by spleen necrosis virus RU5. Journal of virology. Vol. 76, no. 7: 3292-300.

Hull, Stacey; Boris-Lawrie, Kathleen. 2002. RU5 of Mason-Pfizer monkey virus 5' long terminal repeat enhances cytoplasmic expression of human immunodeficiency virus type 1 gag-pol and nonviral reporter RNA. Journal of virology. Vol. 76, no. 20: 10211-8.

Ding, Wei; Kim, Seung-Jae; Nair, Amrithraj, M; Michael, Bindhu; Boris-Lawrie, Kathleen; Tripp, Adam; Feuer, Gerold; Lairmore, Michael D. 2003. Human T-cell lymphotropic virus type 1 p12I enhances interleukin-2 production during T-cell activation. Journal of virology. Vol. 77, no. 20: 11027-39.

Hull, Stacey; Boris-Lawrie, Kathleen. 2003. Analysis of synergy between divergent simple retrovirus posttranscriptional control elements. Virology. Vol. 317, no. 1: 146-54.

Roberts, Tiffiney, M; Boris-Lawrie, Kathleen. 2003. Primary sequence and secondary structure motifs in spleen necrosis virus RU5 confer translational utilization of unspliced human immunodeficiency virus type 1 reporter RNA. Journal of virology. Vol. 77, no. 22: 11973-84.

Altanerova, Veronika; Holicova, Dana; Kucerova, Lucia; Altaner, Cestmir; Lairmore, Michael, D; Boris-Lawrie, Kathleen. 2004. Long-term infection with retroviral structural gene vector provides protection against bovine leukemia virus disease in rabbits. Virology. Vol. 329, no. 2: 434-9.

Michael, Bindhu; Nair, Amrithraj, M; Hiraragi, Hajime; Shen, Lei; Feuer, Gerold; Boris-Lawrie, Kathleen; Lairmore, Michael D. 2004. Human T lymphotropic virus type-1 p30II alters cellular gene expression to selectively enhance signaling pathways that activate T lymphocytes. Retrovirology. Vol. 1: 39.

Nair, Amrithraj; Michael, Bindhu; Hiraragi, Hajime; Fernandez, Soledad; Feuer, Gerold; Boris-Lawrie, Kathleen; Lairmore, Michael. 2005. Human T lymphotropic virus type 1 accessory protein p12I modulates calcium-mediated cellular gene expression and enhances p300 expression in T lymphocytes. AIDS research and human retroviruses. Vol. 21, no. 4: 273-84.

Hartman, Tiffiney Roberts; Qian, Shuiming; Bolinger, Cheryl; Fernandez, Soledad; Schoenberg, Daniel, R; Boris-Lawrie, Kathleen. 2006. RNA helicase A is necessary for translation of selected messenger RNAs. Nature structural & molecular biology. Vol. 13, no. 6: 509-16.

Yilmaz, Alper; Bolinger, Cheryl; Boris-Lawrie, Kathleen. 2006. Retrovirus translation initiation: Issues and hypotheses derived from study of HIV-1. Current HIV research. Vol. 4, no. 2: 131-9.

Yilmaz, Alper; Fernandez, Soledad; Lairmore, Michael, D; Boris-Lawrie, Kathleen. 2006. Coordinate enhancement of transgene transcription and translation in a lentiviral vector. Retrovirology. Vol. 3: 13.

Younis, Ihab; Boris-Lawrie, Kathleen; Green, Patrick L. 2006. Human T-cell leukemia virus open reading frame II encodes a posttranscriptional repressor that is recruited at the level of transcription. Journal of virology. Vol. 80, no. 1: 181-91.

Zhong, Xuehua; Leontis, Neocles; Qian, Shuiming; Itaya, Asuka; Qi, Yijun; Boris-Lawrie, Kathleen; Ding, Biao. 2006. Tertiary structural and functional analyses of a viroid RNA motif by isostericity matrix and mutagenesis reveal its essential role in replication. Journal of virology. Vol. 80, no. 17: 8566-81.

Bolinger, Cheryl; Yilmaz, Alper; Hartman, Tiffiney Roberts; Kovacic, Melinda Butsch; Fernandez, Soledad; Ye, Jianxin; Forget, Mary; Green, Patrick, L; Boris-Lawrie, Kathleen. 2007. RNA helicase A interacts with divergent lymphotropic retroviruses and promotes translation of human T-cell leukemia virus type 1. Nucleic acids research. Vol. 35, no. 8: 2629-42.