OSU:pro

Current OSU Appointment

Assistant Professor, Molecular & Cellular Biochemistry

Chapters In Books

Battle, D.J., Kasim, M., Yong, J. Lotti, F., Lau, C., Mouaikel, J., Han, J., Wan, L. and Dreyfuss, G. 2006. The SMN complex: an assembly machine for RNPs. In Cold Spring Harbor Symposia for Quantitative Biology Vol LXXI - Regulatory RNAs. Cold Spring Harbor, NY: Cold Spring Harbor Press. 313-320.

Degrees

1995	B.A., Johns Hopkins University, Biophysics

1997	M.Philosophy, Yale University, Molecular Biophysics and Biochemistry

2002	Ph.D., Yale University, Molecular Biophysics and Biochemistry

Fellowship, Internship or Residency

2002 - 2008

Postdoctoral Associate, Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, PA, United States.

Peer Reviewed Journal Articles

Battle, Daniel J.; Doudna, Jennifer A. 2001. The stem-loop binding protein forms a highly stable and specific complex with the 3' stem-loop of histone mrnas. RNA (New York). Vol. 7, no. 1: 123-132.

Battle DJ; Doudna JA. 2002. Specificity of RNA-RNA helix recognition. Proceedings Of The National Academy Of Sciences Of The United States Of America. Vol. 99, no. 18. (September 3): 11676.

Yong J; Golembe TJ; Battle DJ; Pellizzoni L; Dreyfuss G. 2004. snRNAs contain specific SMN-binding domains that are essential for snRNP assembly. Molecular And Cellular Biology. Vol. 24, no. 7. (April 1): 2747.

Golembe TJ; Yong J; Battle DJ; Feng W; Wan L; Dreyfuss G. 2005. Lymphotropic Herpesvirus saimiri uses the SMN complex to assemble Sm cores on its small RNAs. Molecular And Cellular Biology. Vol. 25, no. 2. (January 1): 602.

Feng W; Gubitz AK; Wan L; Battle DJ; Dostie J; Golembe TJ; Dreyfuss G. 2005. Gemins modulate the expression and activity of the SMN complex. Human Molecular Genetics. Vol. 14, no. 12. (June 15): 1605.

Wan L; Battle DJ; Yong J; Gubitz AK; Kolb SJ; Wang J; Dreyfuss G. 2005. The survival of motor neurons protein determines the capacity for snRNP assembly: biochemical deficiency in spinal muscular atrophy. Molecular And Cellular Biology. Vol. 25, no. 13. (July 1): 5543.

Battle DJ; Lau CK; Wan L; Deng H; Lotti F; Dreyfuss G. 2006. The Gemin5 protein of the SMN complex identifies snRNAs. Molecular Cell. Vol. 23, no. 2. (July 21): 273.

Kolb SJ; Battle DJ; Dreyfuss G. 2007. Molecular functions of the SMN complex. Journal Of Child Neurology. Vol. 22, no. 8. (August 1): 990.

Battle DJ; Kasim M; Wang J; Dreyfuss G. 2007. SMN-independent subunits of the SMN complex. Identification of a small nuclear ribonucleoprotein assembly intermediate. The Journal Of Biological Chemistry. Vol. 282, no. 38. (September 21): 27953.

Positions

2008 - present

Assistant Professor, The Ohio State University, College of Medicine, Department of Molecular and Cellular Biochemistry. Columbus, OH, United States.

2008 - present

Assistant Professor, The Ohio State University, College of Medicine, Department of Neurology. Columbus, OH, United States.

Presentations

Invited Presentations

Local

Battle, Daniel, Seminar Presenter. 2009. RNA Recognition: Role of Gemin5 in the Biogenesis of Spliceosomal snRNPs. Presented at Bio850, to The Ohio State University Department of Biochemistry. Columbus, OH, USA. (February 13)

International

Battle, Daniel, Presenter. 2005. The SMN complex decodes snRNAs and assembles them into snRNPs. Presented at The Cold Spring Harbor Eukaryotic mRNA Processing Meeting. Cold Spring Harbor, NY, USA.

Battle, Daniel, Presenter. 2006. Gemin5 is the snRNA-binding protein of the SMN complex. Presented at The RNA Society Meeting. Madison, WI, USA.

Other Presentations

International

Battle, Daniel, Poster Presenter. 1999. Biochemical characterization of the SLBP-Histone mRNA complex. Presented at The RNA Society Meeting. Edinburgh, Scottland.

Battle, Daniel, Poster Presenter. 2001. Structural studies of an A-minor RNA-RNA interaction motif. Presented at The RNA Society Meeting. Madison, WI, USA.