OSU:pro

Current OSU Appointment

Professor, Emergency Medicine

Certifications

Diplomat: Emergency Medicine, American Board of Emergency Medicine

Chapters In Books

Angelos M, Janz T. 1990. Cardiopulmonary cerebral resuscitation. In Emergency Medicine: An Approach to Clinical Problem-Solving. Philadelphia, PA: W.B. Saunders Co. p. 39-60.

Angelos MG, Beckley PD. 1996. Newer reperfusion techniques. In Cardiac Arrest: The Pathophysiology and Therapy of Sudden Death. Edited by Paradis NA, Halperin HR, Nowak RM. Baltimore, MD: Williams & Wilkins.

Angelos M. 2002. Original Articles: Laboratory Research. In Introduction to performing peer review of biomedical research. Edited by Neumar RW. Dallas, Texas: American College of Emergency Physicians.

Angelos M. 2007. Invasive Reperfusion Techniques in Cardiac Arrest. In The Science and Practice of Resuscitation Medicine. Cambridge University.

Degrees

1978	B.A.(Honors), University of Utah, Biology

1982	M.D., University of Utah

Editor Reviewed Journal Articles

Angelos MG. 1995. : Choosing the Best Model for Research - Part I. Newsletter from the American College of Emergency Physicians, Emergency Medicine Research Section. Vol. 1. (November 4).

Angelos MG. 1999. Overcoming reperfusion failure in order to treat reperfusion injury. Acad Emerg Med. Vol. 6:77-678.

Angelos MG. 2000. Can We Justify Historical Controls when Using Animal Models?. Ann Emerg Med, no. 36: 622-624.

Angelos MG. 2000. The PULSE Workshop. Society for Academic Emergency Medicine Newsletter. Vol. XII. (January 1): 4:5.

Angelos MG. 2000. The Impact of the EMF/Genetech Center of Excellence Award on the Ohio State Department of Emergency Medicine. Newsletter from the American College of Emergency Physicians, Emergency Medicine Research Section. Vol. 7. (February 1).

Angelos MG. 2002. CPR, ventilation, defibrillation-In what order?. Ann Emerg Med, no. 40(6): 571-574.

Editorial Activities

Book Reviewer

1992	Intensive Care Medicine, eds. Rippe, Irwin,Alpert, Fink. 21:1412, Ann Emergency Medicine.

Consulting Editor

1990 - present

Annals of Emergency Medicine.

Editor

1994 - present

Academic Emergency Medicine.

Journal Reviewer

1986	"Coagulation Studies: Prothrombin Time, Partial Thromboplastin Time, Bleeding Time." Emergency Medicine Clinics of North America. 4:95, 113.

Peer Reviewer

2007 - present

Experimental Gerontology.

2005	Clinica Chimica Acta.

2005	Journal of Neuroscience Methods.

2005

JAMA.

2003 - present

Critical Care Medicine.

2002

JAMA.

2000	Circulation.

1995	Current Therapeutic Research.

1994	Acadenuc Emergency Medicine.

1990 - present

Resuscitation.

Honors

1984	Second Place Award.

1985	First Place Award.

1985	Department of Emergency Medicine Carl Jelenko III, M.D. Academic Excellence Award.

1986 - 1987

Emergency Medicine Foundation/American College of Emergency Physicians Reserach Scholar Award.

1990 - 1991

Emergency Medicin Foundation/Genetech Inc. Career Development Award.

1996	Department of Emergency Medicine Teacher of the Year.

1997	Emergency Medicine Foundation/Genetech Inc. Center of Excellence Award.

2002	Davis Heart Lung Research Institute Investigator.

2004	Faculty Researcher of the Year, Department of Emergency Medicine.

2005	Douglas A. Rund Distinguished Faculty Award, Department of Emergency Medicine.

2006	Top Peer Reviewer.

2006	Outstanding Reviewer.

Licensure

1983 - present

Medical Licensure #35049256: State of Ohio

1985 - present

Medical Licensure #MD-33677-E: State of Pennsylvania

Memberships

1982 - 1992

Member. American Medical Association (AMA)

1982 - 1985

Member. Emergency Medicine Residents Association

1982 - present

Member. American College of Emergency Physicians

1983 - 1986

Member. Society of Teachers in Emergency Medicine

1987 - 1991

Member. Montgomery County Medical Society

1987 - 1989

Member. University Association for Emergency Medicine

1987 - 2005

Member. Society of Critical Care Medicine

1989 - present

Member. Society Academic Emergency Physicians

1989 - present

Member. American Heart Association Cardiopulmonary Council

2005 - present

Member. The American Physiological Society

Papers in Proceedings

1. Safar P, Moossy J, Rao G, Angelos M, Cerchiari E, Gisvold S, Pretto E, Reich H, Vaagenes P, Stezoski S, Alexander H. 1987. "Reversibility of Clinical Death in Animal Outcome Models: The Myth of the Five Minute Limit." In: Proceedings of International Resuscitation Symposium: The Reversibility of Clinical Death. Pittsburgh, PA.

Peer Reviewed Journal Articles

McCabe, J, B; Angelos, M G. 1984. Injury to the head and face in patients with cervical spine injury. The American journal of emergency medicine. Vol. 2, no. 4: 333-5.

ANGELOS M, G; SHEETS C, A; ZYCH P R. 1986. Needle Emboli To Lung Following Intravenous Drug Abuse. Journal of Emergency Medicine. Vol. 4, no. 5: 391-396.

Angelos, M, G; Hamilton, G C. 1986. Coagulation studies: prothrombin time, partial thromboplastin time, bleeding time. Emergency medicine clinics of North America. Vol. 4, no. 1: 95-113.

Angelos, M, G; Sheets, C, A; Zych, P R. 1986. Needle emboli to lung following intravenous drug abuse. The Journal of emergency medicine. Vol. 4, no. 5: 391-6.

Angelos, M, G; Whiteside, K; Hamilton, G C. 1986. Abdominal pain and weakness in an elderly woman. Annals of emergency medicine. Vol. 15, no. 10: 1203-9.

ANGELOS, M; REICH, H; SAFAR, P; STEZOSKI S W. 1987. Coronary Perfusion Pressure During External Cpr Versus Cardiopulmonary Bypass After Prolonged Cardiac Arrest In Dogs. Annals of Emergency Medicine. Vol. 16, no. 10: 1102.

ANGELOS, M; REICH, H; SAFAR, P; STEZOSKI S, W; HOUGHTON F. 1987. Cardiac Resuscitability And Neurologic Recovery After Clinically Relevant Cardiac Arrest Of 20 Min With Cardiopulmonary Bypass Vs. Cardiopulmonary Resuscitation In Dogs. Anesthesiology (Hagerstown). Vol. 67, no. 3A: A147.

ANGELOS M, G; GADDIS M, L; GADDIS G, M; LEASURE J E. 1990. Improved Survival And Reduced Myocardial Necrosis With Cardiopulmonary Bypass Reperfusion In A Canine Model Of Coronary Occlusion And Cardiac Arrest. Annals of Emergency Medicine. Vol. 19, no. 10: 1122-1128.

ANGELOS M, G; GADDIS, M; GADDIS, G; LEASURE J E. 1990. Cardiopulmonary Bypass In A Model Of Acute Myocardial Infarction And Cardiac Arrest. Annals of Emergency Medicine. Vol. 19, no. 8: 874-880.

Angelos, M, G; Gaddis, M, L; Gaddis, G, M; Leasure, J E. 1990. Improved survival and reduced myocardial necrosis with cardiopulmonary bypass reperfusion in a canine model of coronary occlusion and cardiac arrest. Annals of emergency medicine. Vol. 19, no. 10: 1122-8.

Angelos, M, G; Gaddis, M; Gaddis, G; Leasure, J E. 1990. Cardiopulmonary bypass in a model of acute myocardial infarction and cardiac arrest. Annals of emergency medicine. Vol. 19, no. 8: 874-80.

ANGELOS, M; GADDIS, M; GADDIS, G; LEASURE J. 1990. Cardiopulmonary Bypass In A Model Of Acute Myocardial Infarction And Cardiac Arrest. Annals of Emergency Medicine. Vol. 19, no. 5: 605.

Angelos, MG. 1990. The Call to Abstraction. Society for Acadamic Emergency Medicine Newsletter. Vol. 11, no. 8:7.

DEBEHNKE D, J; ANGELOS M G. 1990. Intracranial Hemorrhage And Hemophilia Case Report And Management Guidelines. Journal of Emergency Medicine. Vol. 8, no. 4: 423-428.

DeBehnke, D, J; Angelos, M G. 1990. Intracranial hemorrhage and hemophilia: case report and management guidelines. The Journal of emergency medicine. Vol. 8, no. 4: 423-7.

KOLODZIK J, M; EILERS M, A; ANGELOS M G. 1990. Nonsteroidal Anti-inflammatory Drugs And Coma A Case Report Of Fenoprofen Overdose. Annals of Emergency Medicine. Vol. 19, no. 4: 378-381.

Kolodzik, J, M; Eilers, M, A; Angelos, M G. 1990. Nonsteroidal anti-inflammatory drugs and coma: a case report of fenoprofen overdose. Annals of emergency medicine. Vol. 19, no. 4: 378-81.

REICH, H; ANGELOS, M; SAFAR, P; STERZ, F; LEONOV Y. 1990. Cardiac Resuscitability With Cardiopulmonary Bypass After Increasing Ventricular Fibrillation Times In Dogs. Annals of Emergency Medicine. Vol. 19, no. 8: 887-890.

SAFAR, P; ABRAMSON N, S; ANGELOS, M; CANTADORE, R; LEONOV, Y; LEVINE, R; PRETTO, E; REICH, H; STERZ, F; ET AL. 1990. Emergency Cardiopulmonary Bypass For Resuscitation From Prolonged Cardiac Arrest. American Journal of Emergency Medicine. Vol. 8, no. 1: 55-67.

Whitley, T, W; Spivey, W, H; Abramson, N, S; Angelos, M, G; Barsan, W, G; Bradley, K; Brown, C, G; Cordell, W, H; Dart, R, C; Krause, G S. 1990. A basic resource guide for emergency medicine research. Annals of emergency medicine. Vol. 19, no. 11: 1306-9.

ANGELOS M, G; JANZ T, G; EILERS M, A; HAMILTON G, C; SHEETS C A. 1991. Objectives To Direct The Training Of Emergency Medicine Residents On Off-service Rotations Critical Care Medicine Part 1. Journal of Emergency Medicine. Vol. 9, no. 3: 161-166.

Angelos, M, G; Janz, T, G; Eilers, M, A; Hamilton, G, C; Sheets, C A. 1991. Objectives to direct the training of emergency medicine residents on off-service rotations: critical care medicine, Part 1. The Journal of emergency medicine. Vol. 9, no. 3: 161-6.

ANGELOS, M; SAFAR, P; REICH H. 1991. External Cardiopulmonary Resuscitation Preserves Brain Viability After Prolonged Cardiac Arrest In Dogs. American Journal of Emergency Medicine. Vol. 9, no. 5: 436-443.

DEBEHNKE D, J; ANGELOS M, G; LEASURE J E. 1991. Comparison Of Standard External Cpr Open-chest Cpr And Cardiopulmonary Bypass In A Canine Myocardial Infarct Model. Annals of Emergency Medicine. Vol. 20, no. 7: 754-760.

DeBehnke, D, J; Angelos, M, G; Leasure, J E. 1991. Comparison of standard external CPR, open-chest CPR, and cardiopulmonary bypass in a canine myocardial infarct model. Annals of emergency medicine. Vol. 20, no. 7: 754-60.

Janz, T, G; Angelos, M, G; Eilers, M, A; Sheets, C, A; Hamilton, G C. 1991. Objectives to direct the training of emergency medicine residents on off-service rotations: critical care medicine, Part 2. The Journal of emergency medicine. Vol. 9, no. 4: 281-6.

ANGELOS M, G; DEBEHNKE D, J; LEASURE J E. 1992. Arterial Ph And Carbon Dioxide Tension As Indicators Of Tissue Perfusion During Cardiac Arrest In A Canine Model. Critical Care Medicine. Vol. 20, no. 9: 1302-1308.

Angelos, M, G; DeBehnke, D, J; Leasure, J E. 1992. Arterial blood gases during cardiac arrest: markers of blood flow in a canine model. Resuscitation. Vol. 23, no. 2: 101-11.

Angelos, M, G; DeBehnke, D, J; Leasure, J E. 1992. Arterial pH and carbon dioxide tension as indicators of tissue perfusion during cardiac arrest in a canine model. Critical care medicine. Vol. 20, no. 9: 1302-8.

DEBEHNKE D, J; ANGELOS M, G; LEASURE J E. 1992. Use Of Cardiopulmonary Bypass High-dose Epinephrine And Standard-dose Epinephrine In Resuscitation From Post-countershock Electromechanical Dissociation. Annals of Emergency Medicine. Vol. 21, no. 9: 1051-1057.

DeBehnke, D, J; Angelos, M, G; Leasure, J E. 1992. Use of cardiopulmonary bypass, high-dose epinephrine, and standard-dose epinephrine in resuscitation from post-countershock electromechanical dissociation. Annals of emergency medicine. Vol. 21, no. 9: 1051-7.

Olson, J, E; Hamilton, G, C; Angelos, M, G; Singer, J, I; Eilers, M, E; Gaddis, M. 1992. Objectives to direct the training of emergency medicine residents on off-service rotations: research. The Journal of emergency medicine. Vol. 10, no. 5: 631-6.

Angelos, M, G; Katz-Stein, A; Leasure, J E. 1993. Early detection of myocardial infarction with magnetic resonance imaging in a canine model. Annals of emergency medicine. Vol. 22, no. 9: 1378-84.

Angelos, M, G; Leasure, J, E; Barton, R L. 1993. Fructose-1,6-diphosphate fails to limit early myocardial infarction size in a canine model. Annals of emergency medicine. Vol. 22, no. 2: 171-7.

Angelos, M, G; Ward, K, R; Beckley, P D. 1994. Norepinephrine-induced hypertension following cardiac arrest: effects on myocardial oxygen use in a swine model. Annals of emergency medicine. Vol. 24, no. 5: 907-14.

Angelos, M, G; Ward, K, R; Hobson, J; Beckley, P D. 1994. Organ blood flow following cardiac arrest in a swine low-flow cardiopulmonary bypass model. Resuscitation. Vol. 27, no. 3: 245-54.

Angelos MG. 1995. Right Lung Ventilation during Thoracotomy. Acad Emerg Med. Vol. II: 861-862.

Angelos, M G. 1995. Right lung ventilation during thoracotomy. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. Vol. 2, no. 10: 861-2.

Angelos, M, G; DeBehnke, D J. 1995. Epinephrine and high-flow reperfusion after cardiac arrest in a canine model. Annals of emergency medicine. Vol. 26, no. 2: 208-15.

Angelos, M, G; DeBehnke, D J. 1995. Epinephrine-mediated changes in carbon dioxide tension during reperfusion of ventricular fibrillation in a canine model. Critical care medicine. Vol. 23, no. 5: 925-30.

Angelos, M, G; Griffith, R, F; Beckley, P, D; Rath, D, P; Little, C M. 1995. Myocardial metabolic changes during reperfusion of ventricular fibrillation: a 31P nuclear magnetic resonance study in swine. Critical care medicine. Vol. 23, no. 4: 733-9.

Angelos, M, G; Rath, D, P; Zhu, H; Beckley, P, D; Robitaille, P M. 1999. Flow requirements in ventricular fibrillation: An in vivo nuclear magnetic resonance analysis of the left ventricular high-energy phosphate pool. Annals of emergency medicine. Vol. 34, no. 5: 583-8.

Angelos, M, G; Torres, C, A; Rath, D, P; Zhu, H; Beckley, P, D; Robitaille, P M. 1999. In-vivo myocardial substrate alteration during perfused ventricular fibrillation. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. Vol. 6, no. 6: 581-7.

Angelos, M G. 2000. Can we justify historical control groups when using animal models?. Annals of emergency medicine. Vol. 36, no. 6: 622-4.

Angelos, M, G; Torres, C, A; Waite, M, D; Rath, D, P; Zhu, H; Beckley, P, D; Palmer, B, S; Robitaille, P M. 2000. Left ventricular myocardial adenosine triphosphate changes during reperfusion of ventricular fibrillation: the influence of flow and epinephrine. Critical care medicine. Vol. 28, no. 5: 1503-8.

Angelos, M, G; Menegazzi, J, J; Callaway, C W. 2001. Bench to bedside: resuscitation from prolonged ventricular fibrillation. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. Vol. 8, no. 9: 909-24.

Angelos, Mark, G; Murray, Holt, N; Gorsline, Robert, T; Klawitter, Paul F. 2002. Glucose, insulin and potassium (GIK) during reperfusion mediates improved myocardial bioenergetics. Resuscitation. Vol. 55, no. 3: 329-36.

Angelos, Mark, G; Murray, Holt, N; Waite, Michael, D; Gorsline, Robert T. 2002. Postischemic inotropic support of the dysfunctional heart. Critical care medicine. Vol. 30, no. 2: 410-6.

Angelos, Mark, G; Stoner, Jason D. 2002. Cardiopulmonary resuscitation, ventilation, defibrillation: in what order?. Annals of emergency medicine. Vol. 40, no. 6: 571-4.

Klawitter, Paul, F; Murray, Holt, N; Clanton, Thomas, L; Angelos, Mark G. 2002. Reactive oxygen species generated during myocardial ischemia enable energetic recovery during reperfusion. American journal of physiology. Heart and circulatory physiology. Vol. 283, no. 4: H1656-61.

Klawitter, Paul, F; Murray, Holt, N; Clanton, Thomas, L; Palmer, Brian, S; Angelos, Mark G. 2002. Low flow after global ischemia to improve postischemic myocardial function and bioenergetics. Critical care medicine. Vol. 30, no. 11: 2542-7.

Little, Charles, M; Angelos, Mark, G; Paradis, Norman A. 2003. Compared to angiotensin II, epinephrine is associated with high myocardial blood flow following return of spontaneous circulation after cardiac arrest. Resuscitation. Vol. 59, no. 3: 353-9.

Palmer, Brian, S; Hadziahmetovic, Mersiha; Veci, Timothy; Angelos, Mark G. 2004. Global ischemic duration and reperfusion function in the isolated perfused rat heart. Resuscitation. Vol. 62, no. 1: 97-106.

Palmer, Brian, S; Klawitter, Paul, F; Reiser, Peter, J; Angelos, Mark G. 2004. Degradation of rat cardiac troponin I during ischemia independent of reperfusion. American journal of physiology. Heart and circulatory physiology. Vol. 287, no. 3: H1269-75.

Stoner, Jason, D; Angelos, Mark, G; Clanton, Thomas L. 2004. Myocardial contractile function during postischemic low-flow reperfusion: critical thresholds of NADH and O2 delivery. American journal of physiology. Heart and circulatory physiology. Vol. 286, no. 1: H375-80.

Angelos, Mark, G; Kutala, Vijay, K; Torres, Carlos, A; He, Guanglong; Stoner, Jason, D; Mohammad, Marwan; Kuppusamy, Periannan. 2006. Hypoxic reperfusion of the ischemic heart and oxygen radical generation. American journal of physiology. Heart and circulatory physiology. Vol. 290, no. 1: H341-7.

Corvino, Timothy, F; Nahata, Milap, C; Angelos, Mark, G; Tschampel, Marva, M; Morosco, Richard, S; Zerkle, Jocelyn; Nelson, Richard N. 2006. Availability, stability, and sterility of pralidoxime for mass casualty use. Annals of emergency medicine. Vol. 47, no. 3: 272-7.

Stoner, Jason, D; Clanton, Thomas, L; Aune, Sverre, E; Angelos, Mark G. 2007. O2 delivery and redox state are determinants of compartment-specific reactive O2 species in myocardial reperfusion. American journal of physiology. Heart and circulatory physiology. Vol. 292, no. 1: H109-16.

Angelos MG; Butke RL; Panchal AR; Torres CA; Blumberg A; Schneider JE; Aune SE. 2008. Cardiovascular response to epinephrine varies with increasing duration of cardiac arrest. Resuscitation. Vol. 77, no. 1. (April 1): 101-110. (IF: 2.402)

Angelos MG. 2009. Postarrest nitric oxide effect depends on the source. Critical Care Medicine. Vol. 37, no. 1. (January 1): 368.

Positions

1982 - 1985

Resident, Wright State University, Emergency Medicine. Dayton, OH, United States.

1984 - 1985

Chief Resident, Wright State University, School of Medicine, Department of Emergency Medicine. Dayton, OH, United States.

1985 - 1987

Fellowship, University of Pittsburgh, Critical Care Medicine. Pittsburgh, PA, United States.

1987 - 1991

Assistant Professor, Wright State University, School of Medicine, Department of Emergency Medicine. Dayton, OH, United States.

1987 - 1991

Research Director, Wright State University, Dept Emergency Medicine. Dayton, OH, United States.

1987 - 1991

Journal Club Coordinator, Wright State University, Dept Emergency Medicine. Dayton, OH, United States.

1987 - 1991

ACLS Coordinator, Wright State University, Dept Emergency Medicine. Dayton, OH, United States.

1989 - 1990

Faculty Search Committee, Wright State University, Dept Emergency Medicine. Dayton, OH, United States.

1991 - 1995

Assistant Professor, The Ohio State University, College of Medicine, Department of Emergency Medicine. Columbus, OH, United States.

1993 - present

Fellowship Director, The Ohio State University, Dept of Emergency Medicine. Columbus, OH, United States.

1995 - 2001

Associate Professor, The Ohio State University, College of Medicine, Department of Emergency Medicine. Columbus, OH, United States.

1996 - present

Promotion and Tenure Committee, The Ohio State University. Columbus, OH, United States.

1996 - present

Research Director, The Ohio State University, Dept Emergency Medicine. Columbus, OH, United States.

2001 - present

Professor, The Ohio State University, College of Medicine, Department of Emergency Medicine. Columbus, OH, United States.

2002 - present

Vice Chair for Research, The Ohio State University, Department of Emergency Medicine. Columbus, OH, United States.

2003 - present

Chair, Promotion and Tenure Commitee, The Ohio State University. Columbus, OH, United States.

2003 - present

Department Search Committee, The Ohio State University. Columbus, OH, United States.

2006 - present

Vice Chair Academic Services, The Ohio State University, Department of Emergency Medicine. Columbus, OH, United States.

Reviews

Angelos M. 1988. Review of Principles of Critical Care. Am J Em Med, 6:530.